RESVERATROL PRETREATMENT PROTECTS RAT BRAIN FROM CEREBRAL ISCHEMIC DAMAGE VIA A SIRT1 – UCP2 PATHWAY

Resveratrol is a natural polyphenol found in grapes and wine and has been associated with protective effects against cardiovascular diseases. In vitro, both resveratrol preconditioning (RPC) and ischemic preconditioning (IPC) require activation of sirtuin 1 (SIRT1), an NAD(+)-dependent deacetylases,...

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Autores principales: Della-Morte, David, Dave, Kunjan R., DeFazio, R. Anthony, Bao, Ying Chun, Raval, Ami P., Perez-Pinzon, Miguel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668125/
https://ncbi.nlm.nih.gov/pubmed/19356683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.01.017
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