RESVERATROL PRETREATMENT PROTECTS RAT BRAIN FROM CEREBRAL ISCHEMIC DAMAGE VIA A SIRT1 – UCP2 PATHWAY

Resveratrol is a natural polyphenol found in grapes and wine and has been associated with protective effects against cardiovascular diseases. In vitro, both resveratrol preconditioning (RPC) and ischemic preconditioning (IPC) require activation of sirtuin 1 (SIRT1), an NAD(+)-dependent deacetylases,...

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Autori principali: Della-Morte, David, Dave, Kunjan R., DeFazio, R. Anthony, Bao, Ying Chun, Raval, Ami P., Perez-Pinzon, Miguel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668125/
https://ncbi.nlm.nih.gov/pubmed/19356683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.01.017
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