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RESVERATROL PRETREATMENT PROTECTS RAT BRAIN FROM CEREBRAL ISCHEMIC DAMAGE VIA A SIRT1 – UCP2 PATHWAY

Resveratrol is a natural polyphenol found in grapes and wine and has been associated with protective effects against cardiovascular diseases. In vitro, both resveratrol preconditioning (RPC) and ischemic preconditioning (IPC) require activation of sirtuin 1 (SIRT1), an NAD(+)-dependent deacetylases,...

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Detalhes bibliográficos
Main Authors: Della-Morte, David, Dave, Kunjan R., DeFazio, R. Anthony, Bao, Ying Chun, Raval, Ami P., Perez-Pinzon, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668125/
https://ncbi.nlm.nih.gov/pubmed/19356683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.01.017
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