Inhibition of β-Catenin Signaling in Articular Chondrocytes Results in Articular Cartilage Destruction

OBJECTIVE: Osteoarthritis is a degenerative joint disease whose molecular mechanism is currently unknown. Wnt/β-catenin signaling has been demonstrated to play a critical role in the development and function of articular chondrocytes. To determine the role of β-catenin signaling in articular chondro...

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Hlavní autoři: Zhu, Mei, Chen, Mo, Zuscik, Michael, Wu, Qiuqian, Wang, Yong-Jun, Rosier, Randy N., O’Keefe, Regis J., Chen, Di
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667964/
https://ncbi.nlm.nih.gov/pubmed/18576323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23614
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