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Virus free induction of pluripotency and subsequent excision of reprogramming factors
Reprogramming of somatic cells to pluripotency, thereby creating induced pluripotent stem (iPS) cells, promises to transform regenerative medicine. Most instances of direct reprogramming have been achieved by forced expression of defined factors using multiple viral vectors1-7. However, such iPS cel...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667910/ https://ncbi.nlm.nih.gov/pubmed/19252477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07864 |
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