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Potential Hepatotoxicity of Efavirenz and Saquinavir/Ritonavir Coadministration in Healthy Volunteers

OBJECTIVE: This study was designed to investigate the pharmacokinetic effects of coadministration of saquinavir/ritonavir with efavirenz at steady state. METHODS: Healthy volunteers in this open-label, two-arm, one-sequence, two-period crossover study (planned enrollment of 40 participants) were ran...

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Autors principals: Jamois, Candice, Riek, Myriam, Schmitt, Christophe
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667896/
https://ncbi.nlm.nih.gov/pubmed/19381337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2009.00016.x
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