Mamu-A*01/K(b) Transgenic and MHC Class I Knockout Mice as a Tool for HIV Vaccine Development

We have developed a murine model expressing the rhesus macaque (RM) Mamu-A*01 MHC allele to characterize immune responses and vaccines based on antigens of importance to human disease processes. Towards that goal, transgenic (Tg) mice expressing chimeric RM (α1 and α2 Mamu-A*01 domains) and murine (...

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Main Authors: Li, Jinliang, Srivastava, Tumul, Rawal, Ravindra, Manuel, Edwin, Isbell, Donna, Tsark, Walter, La Rosa, Corinna, Wang, Zhongde, Li, Zhongqi, Barry, Peter A., Hagen, Katherine, Longmate, Jeffrey, Diamond, Don J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667874/
https://ncbi.nlm.nih.gov/pubmed/19249807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.01.041
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