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A novel approach to evaluate the immunogenicity of viral antigens of clinical importance in HLA transgenic murine models
Transgenic (Tg) mice expressing HLA class I alleles and lacking murine MHC class I represent a useful model for the pre-clinical evaluation of human vaccines, which focus on induction of CD8(+) T-cell responses. We have developed a platform to be used in Tg mice for exploring the immunogenicity of T...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577668/ https://ncbi.nlm.nih.gov/pubmed/18706443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2008.07.010 |
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