Significance of 14-3-3 Self-Dimerization for Phosphorylation-dependent Target Binding

14-3-3 proteins via binding serine/threonine-phosphorylated proteins regulate diverse intracellular processes in all eukaryotic organisms. Here, we examine the role of 14-3-3 self-dimerization in target binding, and in the susceptibility of 14-3-3 to undergo phosphorylation. Using a phospho-specific...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Shen, Ying H., Godlewski, Jakub, Bronisz, Agnieszka, Zhu, Jun, Comb, Michael J., Avruch, Joseph, Tzivion, Guri
Format: Artigo
Language:Inglês
Published: American Society for Cell Biology 2003
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC266786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14551260/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-12-0821
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