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PIKfyve Controls Fluid Phase Endocytosis but Not Recycling/Degradation of Endocytosed Receptors or Sorting of Procathepsin D by Regulating Multivesicular Body Morphogenesis

The mammalian phosphatidylinositol (PtdIns) 5-P/PtdIns 3,5-P(2)–producing kinase PIKfyve has been implicated in maintaining endomembrane homeostasis in mammalian cells. To address the role of PIKfyve in trafficking processes, we examined the functioning of the biosynthetic, endocytic, and recycling...

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Publikašuvnnas:Mol Biol Cell
Váldodahkkit: Ikonomov, Ognian C., Sbrissa, Diego, Foti, Michelangelo, Carpentier, Jean-Louis, Shisheva, Assia
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Cell Biology 2003
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC266774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14551253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-04-0222
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