Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement

Amplification of the complement cascade through the alternative pathway can lead to excessive inflammation. Targeting C3b, a component central to the alternative pathway of complement, provides a powerful approach to inhibit complement-mediated immune responses and tissue injury. In the present stud...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Katschke, Kenneth J., Stawicki, Scott, Yin, Jianping, Steffek, Micah, Xi, Hongkang, Sturgeon, Lizette, Hass, Philip E., Loyet, Kelly M., DeForge, Laura, Wu, Yan, van Lookeren Campagne, Menno, Wiesmann, Christian
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Protein Structure and Folding
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667734/
https://ncbi.nlm.nih.gov/pubmed/19196712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809106200
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items