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Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter

OBJECTIVES: The aim of this study was to investigate the feasibility and efficacy of antisense-mediated gene silencing by peptide nucleic acid (PNA) for specific inactivation of the CmeABC multidrug efflux transporter in Campylobacter jejuni. METHODS: PNA was designed to bind to the cmeA transcript...

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Detalles Bibliográficos
Main Authors: Jeon, Byeonghwa, Zhang, Qijing
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667136/
https://ncbi.nlm.nih.gov/pubmed/19279049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp067
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