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Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter
OBJECTIVES: The aim of this study was to investigate the feasibility and efficacy of antisense-mediated gene silencing by peptide nucleic acid (PNA) for specific inactivation of the CmeABC multidrug efflux transporter in Campylobacter jejuni. METHODS: PNA was designed to bind to the cmeA transcript...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667136/ https://ncbi.nlm.nih.gov/pubmed/19279049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp067 |
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