Target optimization for peptide nucleic acid (PNA)-mediated antisense inhibition of the CmeABC multidrug efflux pump in Campylobacter jejuni

OBJECTIVES: CmeABC is a resistance-nodulation-cell division (RND)-type multidrug efflux pump conferring resistance to clinically important antibiotics in Campylobacter. This study aimed to identify the optimal target sites for the inhibition of CmeABC with antisense peptide nucleic acid (PNA). METHO...

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Bibliografiska uppgifter
Huvudupphovsmän: Oh, Euna, Zhang, Qijing, Jeon, Byeonghwa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886934/
https://ncbi.nlm.nih.gov/pubmed/24084637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt381
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