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Target optimization for peptide nucleic acid (PNA)-mediated antisense inhibition of the CmeABC multidrug efflux pump in Campylobacter jejuni

OBJECTIVES: CmeABC is a resistance-nodulation-cell division (RND)-type multidrug efflux pump conferring resistance to clinically important antibiotics in Campylobacter. This study aimed to identify the optimal target sites for the inhibition of CmeABC with antisense peptide nucleic acid (PNA). METHO...

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Detalhes bibliográficos
Main Authors: Oh, Euna, Zhang, Qijing, Jeon, Byeonghwa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886934/
https://ncbi.nlm.nih.gov/pubmed/24084637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt381
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