Quantification of the Thermodynamically Linked Quaternary and Tertiary Structural Stabilities of Transthyretin and its Disease-Associated Variants–the Relationship between Stability and Amyloidosis

Urea denaturation studies were carried out as a function of transthyretin (TTR) concentration to quantify the thermodynamically linked quaternary and tertiary structural stability and to better understand the relationship between mutant folding energetics and amyloid disease phenotype. Urea denatura...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Hurshman Babbes, Amy R., Powers, Evan T., Kelly, Jeffery W.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667099/
https://ncbi.nlm.nih.gov/pubmed/18537267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800636q
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki