Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer

BACKGROUND: UbcH10 participates in proper metaphase to anaphase transition, and abrogation of UbcH10 results in the premature separation of sister chromatids. To assess the potential role of UbcH10 in colon cancer progression, we analyzed the clinicopathological relevance of UbcH10 in colon cancer....

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Main Authors: Fujita, Takeo, Ikeda, Hirokuni, Taira, Naruto, Hatoh, Shinji, Naito, Minoru, Doihara, Hiroyoshi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666760/
https://ncbi.nlm.nih.gov/pubmed/19302711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-87
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