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UbcH10 overexpression increases carcinogenesis and blocks ALLN susceptibility in colorectal cancer

Cyclins are essential for cell proliferation, the cell cycle and tumorigenesis in all eukaryotes. UbcH10 regulates the degradation of cyclins in a ubiquitin-dependent manner. Here, we report that UbcH10 is likely involved in tumorigenesis. We found that cancer cells exposed to n-acetyl-leu-leu-norle...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Shang-Ze, Song, Yang, Zhang, Hui-Hui, Jin, Bing-Xue, Liu, Yi, Liu, Wen-Bin, Zhang, Xiao-Dong, Du, Run-Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223683/
https://ncbi.nlm.nih.gov/pubmed/25376843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06910
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