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Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and 2 cholecystokinin receptors

Radiolabeled antagonists of specific peptide receptors identify a higher number of receptor binding sites than agonists and may thus be preferable for in vivo tumor targeting. In this study, two novel radioiodinated 1,4-benzodiazepines, (S)-1-(3-iodophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Akgün, Eyup, Körner, Meike, Gao, Fan, Harkumar, Kaleeckal G., Waser, Beatrice, Reubi, Jean Claude, Portoghese, Philip S., Miller, Laurence J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666544/
https://ncbi.nlm.nih.gov/pubmed/19271701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801439x
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