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Unexpected Expression Pattern of Tetracycline-Regulated Transgenes in Mice

In generating a conditional transgenic murine model based on a tetracycline-regulated system, we obtained unexpected patterns of expression due to the transcriptional inactivity of the tet-responder promoter. Here we show strong cell-type-restricted expression that was variegated to an extent determ...

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Detalhes bibliográficos
Principais autores: Bao-Cutrona, M., Moral, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666531/
https://ncbi.nlm.nih.gov/pubmed/19204377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.097600
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