A Mathematical Model Gives Insights into the Effects of Vitamin B-6 Deficiency on 1-Carbon and Glutathione Metabolism

We experimented with a mathematical model for 1-carbon metabolism and glutathione (GSH) synthesis to investigate the effects of vitamin B-6 deficiency on the reaction velocities and metabolite concentrations in this metabolic network. The mathematical model enabled us to independently alter the acti...

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Bibliografiske detaljer
Main Authors: Nijhout, H. Frederik, Gregory, Jesse F., Fitzpatrick, Courtney, Cho, Eugenia, Lamers, K. Yvonne, Ulrich, Cornelia M., Reed, Michael C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Nutrition 2009
Fag:
Methodology and Mathematical Modeling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666368/
https://ncbi.nlm.nih.gov/pubmed/19244383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.109.104265
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