MATHEMATICAL MODELING PREDICTS THE EFFECT OF FOLATE DEFICIENCY AND EXCESS ON CANCER RELATED BIOMARKERS

BACKGROUND: Folate is an essential B-vitamin that mediates one-carbon metabolism reactions, including nucleotide synthesis and others related to carcinogenesis. Both low and high folate status influences carcinogenesis. METHODS: We used a mathematical model of folate-mediated one-carbon metabolism t...

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Auteurs principaux: Neuhouser, Marian L., Nijhout, H. Frederik, Gregory, Jesse F., Reed, Michael C., James, S. Jill, Liu, Amy, Shane, Barry, Ulrich, Cornelia M.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169720/
https://ncbi.nlm.nih.gov/pubmed/21752986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-1352
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