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Mathematical modeling of the effects of glutathione on arsenic methylation

BACKGROUND: Arsenic is a major environmental toxin that is detoxified in the liver by biochemical mechanisms that are still under study. In the traditional metabolic pathway, arsenic undergoes two methylation reactions, each followed by a reduction, after which it is exported and released in the uri...

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Bibliographic Details
Main Authors: Lawley, Sean D, Yun, Jina, Gamble, Mary V, Hall, Megan N, Reed, Michael C, Nijhout, H Frederik
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041632/
https://ncbi.nlm.nih.gov/pubmed/24885596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-11-20
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