GCN5 is a required cofactor for a ubiquitin ligase that targets NF-κB/RelA

The transcription factor NF-κB is a critical regulator of inflammatory and cell survival signals. Proteasomal degradation of NF-κB subunits plays an important role in the termination of NF-κB activity, and at least one of the identified ubiquitin ligases is a multimeric complex containing Copper Met...

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Main Authors: Mao, Xicheng, Gluck, Nathan, Li, Duo, Maine, Gabriel N., Li, Haiying, Zaidi, Iram W., Repaka, Aparna, Mayo, Marty W., Burstein, Ezra
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666342/
https://ncbi.nlm.nih.gov/pubmed/19339690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1748409
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