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Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1

The majority of patients with lung cancer present with metastatic disease. Chronic inflammation and subsequent activation of NF-κB have been associated the development of cancers. The RelA/p65 subunit of NF-κB is typically associated with transcriptional activation. In this report we show that RelA/...

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Detalhes bibliográficos
Main Authors: Liu, Yuan, Mayo, Marty W., Nagji, Alykhan S., Smith, Philip W., Ramsey, Catherine S., Li, Duo, Jones, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219802/
https://ncbi.nlm.nih.gov/pubmed/21765477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.308
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