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The structure of Interleukin-23 reveals the molecular basis of p40 subunit sharing with IL-12
Interleukin-23 is a recently identified member of the IL-12 family of heterodimeric cytokines that modulate subpopulations of T helper cells, and both IL-12 and IL-23 are attractive targets for therapy of autoimmune diseases. IL-23 is a binary complex of a four-helix bundle cytokine (p19) and a solu...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666310/ https://ncbi.nlm.nih.gov/pubmed/18680750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.07.051 |
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