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Mechanism of Genomic Instability in Cells Infected with the High-Risk Human Papillomaviruses

In HPV–related cancers, the “high-risk” human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV fragments express viral oncoproteins and carry an origin of DNA replication that is capable of initiating bidirectional DNA re-replication in...

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Detalhes bibliográficos
Main Authors: Kadaja, Meelis, Isok-Paas, Helen, Laos, Triin, Ustav, Ene, Ustav, Mart
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666264/
https://ncbi.nlm.nih.gov/pubmed/19390600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000397
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