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Mechanism of Genomic Instability in Cells Infected with the High-Risk Human Papillomaviruses

In HPV–related cancers, the “high-risk” human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV fragments express viral oncoproteins and carry an origin of DNA replication that is capable of initiating bidirectional DNA re-replication in...

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Hlavní autoři: Kadaja, Meelis, Isok-Paas, Helen, Laos, Triin, Ustav, Ene, Ustav, Mart
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666264/
https://ncbi.nlm.nih.gov/pubmed/19390600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000397
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