Recombination-Dependent Oligomerization of Human Papillomavirus Genomes upon Transient DNA Replication

We describe the extensive and progressive oligomerization of human papillomavirus (HPV) genomes after transfection into the U2OS cell line. The HPV genomic oligomers are extrachromosomal concatemeric molecules containing the viral genome in a head-to-tail orientation. The process of oligomerization...

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Main Authors: Orav, Marit, Henno, Liisi, Isok-Paas, Helen, Geimanen, Jelizaveta, Ustav, Mart, Ustav, Ene
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807893/
https://ncbi.nlm.nih.gov/pubmed/23986589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01798-13
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