Recombination-Dependent Oligomerization of Human Papillomavirus Genomes upon Transient DNA Replication

We describe the extensive and progressive oligomerization of human papillomavirus (HPV) genomes after transfection into the U2OS cell line. The HPV genomic oligomers are extrachromosomal concatemeric molecules containing the viral genome in a head-to-tail orientation. The process of oligomerization...

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Detalhes bibliográficos
Main Authors: Orav, Marit, Henno, Liisi, Isok-Paas, Helen, Geimanen, Jelizaveta, Ustav, Mart, Ustav, Ene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807893/
https://ncbi.nlm.nih.gov/pubmed/23986589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01798-13
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