Tumor-growth–promoting cyclooxygenase-2 prostaglandin E(2) pathway provides medulloblastoma therapeutic targets

Prostaglandin E(2) (PGE(2)) has been shown to play important roles in several aspects of tumor development and progression. PGE(2) is synthesized from arachidonic acid by cyclooxygenases (COX) and prostaglandin E synthases (PGES) and mediates its biological activity through binding to the four prost...

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Detalles Bibliográficos
Main Authors: Baryawno, Ninib, Sveinbjörnsson, Baldur, Eksborg, Staffan, Orrego, Abiel, Segerström, Lova, Öqvist, Carl Otto, Holm, Stefan, Gustavsson, Bengt, Kågedal, Bertil, Kogner, Per, Johnsen, John Inge
Formato: Artigo
Idioma:Inglês
Publicado: Duke University Press 2008
Assuntos:
Basic and Translational Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666243/
https://ncbi.nlm.nih.gov/pubmed/18715952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-035
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