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Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1

This study questioned the role of paraoxonase 2 (PON2) in attenuation of macrophage lipids accumulation. Mouse peritoneal macrophages (MPMs) harvested from PON2-deficient mice versus control C57BL/6 mice, look like foam cells and were larger in size and filled with lipid droplets. Macrophage triglyc...

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Hlavní autoři: Rosenblat, Mira, Coleman, Raymond, Reddy, Srinivasa T., Aviram, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666173/
https://ncbi.nlm.nih.gov/pubmed/19091699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800550-JLR200
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