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Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1

This study questioned the role of paraoxonase 2 (PON2) in attenuation of macrophage lipids accumulation. Mouse peritoneal macrophages (MPMs) harvested from PON2-deficient mice versus control C57BL/6 mice, look like foam cells and were larger in size and filled with lipid droplets. Macrophage triglyc...

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Detalhes bibliográficos
Main Authors: Rosenblat, Mira, Coleman, Raymond, Reddy, Srinivasa T., Aviram, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666173/
https://ncbi.nlm.nih.gov/pubmed/19091699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800550-JLR200
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