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Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

HDL levels are inversely related to the risk of developing atherosclerosis. In serum, paraoxonase (PON) is associated with HDL, and was shown to inhibit LDL oxidation. Whether PON also protects HDL from oxidation is unknown, and was determined in the present study. In humans, we found serum HDL PON...

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Main Authors: Aviram, M, Rosenblat, M, Bisgaier, C L, Newton, R S, Primo-Parmo, S L, La Du, B N
格式: Artigo
語言:Inglês
出版: 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC508738/
https://ncbi.nlm.nih.gov/pubmed/9541487
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