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Mechanisms of triglyceride accumulation in activated macrophages

LPS treatment of macrophages induces TG accumulation, which is accentuated by TG-rich lipoproteins or FFA. We defined pathways altered during macrophage activation that contribute to TG accumulation. Glucose uptake increased with activation, accompanied by increased GLUT1. Oxidation of glucose marke...

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Detalhes bibliográficos
Main Authors: Feingold, Kenneth R., Shigenaga, Judy K., Kazemi, Mahmood R., McDonald, Carol M., Patzek, Sophie M., Cross, Andrew S., Moser, Arthur, Grunfeld, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441312/
https://ncbi.nlm.nih.gov/pubmed/22753953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1111537
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