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LPS and proinflammatory cytokines decrease lipin-1 in mouse adipose tissue and 3T3-L1 adipocytes

Infection and inflammation affect adipose triglyceride metabolism, resulting in increased plasma free fatty acid (FFA) and VLDL levels during the acute-phase response. Lipin-1, a multifunctional protein, plays a critical role in adipose differentiation, mitochondrial oxidation, and triglyceride synt...

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Autors principals: Lu, Biao, Lu, Yang, Moser, Arthur H., Shigenaga, Judy K., Grunfeld, Carl, Feingold, Kenneth R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603550/
https://ncbi.nlm.nih.gov/pubmed/18940942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90323.2008
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