Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

The p53 protein is critical for multiple cellular functions including cell growth and DNA repair. We assessed whether polymorphisms in the region encoding TP53 were associated with risk of invasive ovarian cancer. The study population includes a total of 5,206 invasive ovarian cancer cases (2,829 of...

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Autors principals: Schildkraut, Joellen M., Goode, Ellen L, Clyde, Merlise A., Iversen, Edwin S., Moorman, Patricia G., Berchuck, Andrew, Marks, Jeffrey R., Lissowska, Jolanta, Brinton, Louise, Peplonska, Beata, Cunningham, Julie M., Vierkant, Robert A., Rider, David N., Chenevix-Trench, Georgia, Webb, Penelope M., Beesley, Jonathan, Chen, Xiaoqing, Phelan, Catherine, Sutphen, Rebecca, Sellers, Thomas A., Pearce, Leigh, Wu, Anna H., Van Den Berg, David, Conti, David, Elund, Christopher K., Anderson, Rebecca, Goodman, Marc T., Lurie, Galina, Carney, Michael E., Thompson, Pamela J., Gayther, Simon A., Ramus, Susan J., Jacobs, Ian, Kjaer, Susanne Krüger, Hogdall, Estrid, Blaakaer, Jan, Hogdall, Claus, Easton, Douglas F., Song, Honglin, Pharoah, Paul D.P., Whittemore, Alice S., McGuire, Valerie, Quaye, Lydia, Anton-Culver, Hoda, Ziogas, Argyrios, Terry, Kathryn L., Cramer, Daniel W., Hankinson, Susan E., Tworoger, Shelley S., Calingaert, Brian, Chanock, Stephen, Sherman, Mark, Garcia-Closason, Montserrat
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666150/
https://ncbi.nlm.nih.gov/pubmed/19276375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2902
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