Association Between Single-Nucleotide Polymorphisms in Hormone Metabolism and DNA Repair Genes and Epithelial Ovarian Cancer: Results from Two Australian Studies and an Additional Validation Set

Although some high-risk ovarian cancer genes have been identified, it is likely that common low penetrance alleles exist that confer some increase in ovarian cancer risk. We have genotyped nine putative functional single-nucleotide polymorphisms (SNP) in genes involved in steroid hormone synthesis (...

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Main Authors: Beesley, Jonathan, Jordan, Susan J., Spurdle, Amanda B., Song, Honglin, Ramus, Susan J., Kjaer, Suzanne Kruger, Hogdall, Estrid, DiCioccio, Richard A., McGuire, Valerie, Whittemore, Alice S., Gayther, Simon A., Pharoah, Paul D.P., Webb, Penelope M., Chenevix-Trench, Georgia
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666187/
https://ncbi.nlm.nih.gov/pubmed/18086758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-07-0542
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