Role of genetic polymorphisms and ovarian cancer susceptibility

The value of identifying women with an inherited predisposition to epithelial ovarian cancer has become readily apparent with the identification of the BRCA1, and BRCA2 genes. Women who inherit a deleterious mutation in either of these genes have a very high lifetime risk of ovarian cancer (10–60%)...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Fasching, Peter A., Gayther, Simon, Pearce, Leigh, Schildkraut, Joellen M., Goode, Ellen, Thiel, Falk, Chenevix-Trench, Georgia, Chang-Claude, Jenny, Wang-Gohrke, Shan, Ramus, Susan, Pharoah, Paul, Berchuck, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2009
Assuntos:
Thematic Issue Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527888/
https://ncbi.nlm.nih.gov/pubmed/19383379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2009.01.008
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