Role of genetic polymorphisms and ovarian cancer susceptibility

The value of identifying women with an inherited predisposition to epithelial ovarian cancer has become readily apparent with the identification of the BRCA1, and BRCA2 genes. Women who inherit a deleterious mutation in either of these genes have a very high lifetime risk of ovarian cancer (10–60%)...

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Опубликовано в: :Mol Oncol
Главные авторы: Fasching, Peter A., Gayther, Simon, Pearce, Leigh, Schildkraut, Joellen M., Goode, Ellen, Thiel, Falk, Chenevix-Trench, Georgia, Chang-Claude, Jenny, Wang-Gohrke, Shan, Ramus, Susan, Pharoah, Paul, Berchuck, Andrew
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2009
Предметы:
Thematic Issue Reviews
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527888/
https://ncbi.nlm.nih.gov/pubmed/19383379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2009.01.008
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