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Differential Requirement for MEK/ERK and SMAD Signaling in PAI-1 and CTGF Expression in Response to Microtubule Disruption

Colchicine and nocodazole, both established microtubule disruptors, are useful tools to investigate cytoskeletal-dependent signaling cascades and the associated downstream transcriptional targets. Since cytoskeletal events impact pathophysiologic consequences in the vascular system, the signaling re...

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Detalhes bibliográficos
Main Authors: Samarakoon, Rohan, Higgins, Craig E., Higgins, Stephen P., Higgins, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666018/
https://ncbi.nlm.nih.gov/pubmed/19249354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.02.007
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