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Aberrant Heparan Sulfate Proteoglycan Localization, Despite Normal Exostosin, in Central Chondrosarcoma

The tumor suppressor genes EXT1 and EXT2 are involved in the formation of multiple osteochondromas, which can progress to become secondary peripheral chondrosarcomas. The most common chondrosarcoma subtype is primary central chondrosarcoma, which occurs in the medullar cavity of bone. The EXT1/EXT2...

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Autores principales: Schrage, Yvonne M., Hameetman, Liesbeth, Szuhai, Karoly, Cleton-Jansen, Anne-Marie, Taminiau, Antonie H.M., Hogendoorn, Pancras C.W., Bovée, Judith V.M.G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665757/
https://ncbi.nlm.nih.gov/pubmed/19179614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080623
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