Aberrant Heparan Sulfate Proteoglycan Localization, Despite Normal Exostosin, in Central Chondrosarcoma

The tumor suppressor genes EXT1 and EXT2 are involved in the formation of multiple osteochondromas, which can progress to become secondary peripheral chondrosarcomas. The most common chondrosarcoma subtype is primary central chondrosarcoma, which occurs in the medullar cavity of bone. The EXT1/EXT2...

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Main Authors: Schrage, Yvonne M., Hameetman, Liesbeth, Szuhai, Karoly, Cleton-Jansen, Anne-Marie, Taminiau, Antonie H.M., Hogendoorn, Pancras C.W., Bovée, Judith V.M.G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665757/
https://ncbi.nlm.nih.gov/pubmed/19179614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080623
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