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HMGA2 Maintains Oncogenic RAS-Induced Epithelial-Mesenchymal Transition in Human Pancreatic Cancer Cells

Pancreatic cancer is a highly aggressive malignancy due to elevated mitotic activities and epithelial-mesenchymal transition (EMT). Oncogenic RAS and transforming growth factor-β signaling are implicated in these malignant features. The mechanisms that underlie EMT need to be addressed since it prom...

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Bibliographic Details
Main Authors: Watanabe, Sugiko, Ueda, Yasuaki, Akaboshi, Shin-ichi, Hino, Yuko, Sekita, Yoko, Nakao, Mitsuyoshi
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665746/
https://ncbi.nlm.nih.gov/pubmed/19179606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080523
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