Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin

The capacity of the immunomodulatory drug rapamycin (RAPA) to inhibit replication of the CCR5 strain of human immunodeficiency virus (HIV) in vitro prompted us to test its effects in a murine preclinical model of HIV infection. RAPA (0·6 or 6 mg/kg body weight) or its vehicle were administered daily...

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Bibliografiset tiedot
Päätekijät: Nicoletti, F, Lamenta, C, Donati, S, Spada, M, Ranazzi, A, Cacopardo, B, Mangano, K, Belardelli, F, Perno, C, Aquaro, S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2009
Aiheet:
Translational Studies
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665676/
https://ncbi.nlm.nih.gov/pubmed/19076826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03780.x
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