Dermal Microvascular Injury in the Human Peripheral Blood Lymphocyte Reconstituted-Severe Combined Immunodeficient (HuPBL-SCID) Mouse/Skin Allograft Model Is T Cell Mediated and Inhibited by a Combination of Cyclosporine and Rapamycin

We have analyzed the mechanism of human endothelial injury in a human peripheral blood lymphocyte-severe combined immunodeficient (huPBL-SCID) mouse/human skin graft model of allograft injury and examined the effect of immunosuppressive drugs on this process. In this model, split-thickness human ski...

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Bibliografiske detaljer
Main Authors: Murray, Allan G., Schechner, Jeffrey S., Epperson, Diane E., Sultan, Parvez, McNiff, Jennifer M., Hughes, Christopher C. W., Lorber, Marc I., Askenase, Philip W., Pober, Jordan S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 1998
Fag:
Animal Models
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852982/
https://ncbi.nlm.nih.gov/pubmed/9708821
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