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Reconstitution of huPBL-NSG Mice with Donor-Matched Dendritic Cells Enables Antigen-Specific T-cell Activation

Humanized mouse models provide a unique opportunity to study human immune cells in vivo, but traditional models have been limited to the evaluation of non-specific T-cell interactions due to the absence of antigen-presenting cells. In this study, immunodeficient NOD/SCID/IL2r-γ(null) (NSG) mice were...

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Bibliografiska uppgifter
Huvudupphovsmän: Harui, Airi, Kiertscher, Sylvia M., Roth, Michael D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028099/
https://ncbi.nlm.nih.gov/pubmed/20532647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-010-9223-x
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