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Aberrant Forkhead Box O1 Function Is Associated with Impaired Hepatic Metabolism

FoxO1 plays an important role in mediating the effect of insulin on hepatic metabolism. Increased FoxO1 activity is associated with reduced ability of insulin to regulate hepatic glucose production. However, the underlying mechanism and physiology remain unknown. We studied the effect of FoxO1 on th...

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Autori principali: Qu, Shen, Altomonte, Jennifer, Perdomo, German, He, Jing, Fan, Yong, Kamagate, Adama, Meseck, Marcia, Dong, H. Henry
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665253/
https://ncbi.nlm.nih.gov/pubmed/16997836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-0541
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