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Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice

Alexander disease is a fatal leukoencephalopathy caused by dominantly-acting coding mutations in GFAP. Previous work has also implicated elevations in absolute levels of GFAP as central to the pathogenesis of the disease. However, identification of the critical astrocyte functions that are compromis...

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Detalhes bibliográficos
Main Authors: Cho, Woosung, Messing, Albee
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665202/
https://ncbi.nlm.nih.gov/pubmed/19146851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.12.012
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