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Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice
Alexander disease is a fatal leukoencephalopathy caused by dominantly-acting coding mutations in GFAP. Previous work has also implicated elevations in absolute levels of GFAP as central to the pathogenesis of the disease. However, identification of the critical astrocyte functions that are compromis...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665202/ https://ncbi.nlm.nih.gov/pubmed/19146851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.12.012 |
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