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Differential Clathrin Binding and Subcellular Localization of OCRL1 Splice Isoforms

Mutation of the inositol polyphosphate 5-phosphatase OCRL1 causes the X-linked disorder oculocerebrorenal syndrome of Lowe, characterized by defects in the brain, kidneys, and eyes. OCRL1 exists as two splice isoforms that differ by a single exon encoding 8 amino acids. The longer protein, termed is...

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Detalhes bibliográficos
Main Authors: Choudhury, Rawshan, Noakes, Christopher J., McKenzie, Edward, Kox, Corinne, Lowe, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665120/
https://ncbi.nlm.nih.gov/pubmed/19211563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807442200
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