Location of the Retinal Chromophore in the Activated State of Rhodopsin(*)

Rhodopsin is a highly specialized G protein-coupled receptor (GPCR) that is activated by the rapid photochemical isomerization of its covalently bound 11-cis-retinal chromophore. Using two-dimensional solid-state NMR spectroscopy, we defined the position of the retinal in the active metarhodopsin II...

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Bibliografiske detaljer
Main Authors: Ahuja, Shivani, Crocker, Evan, Eilers, Markus, Hornak, Viktor, Hirshfeld, Amiram, Ziliox, Martine, Syrett, Natalie, Reeves, Philip J., Khorana, H. Gobind, Sheves, Mordechai, Smith, Steven O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665073/
https://ncbi.nlm.nih.gov/pubmed/19176531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805725200
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