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Multivalency-Assisted Control of Intracellular Signaling Pathways: Application for Ubiquitin-Dependent N-End Rule Pathway
Intracellular signaling is often mediated by a family of functionally overlapping signal mediators that contain multiple sites interacting with other proteins or ligands with weak affinity (K(d) > μM). Conjugation of multiple low-affinity ligands into a high-affinity multivalent molecule provides...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665046/ https://ncbi.nlm.nih.gov/pubmed/19246002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.01.012 |
| Etiketak: |
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